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Treatment centers
& Support

Actor portrayal. MLD is a recessive inherited disease.
Actor portrayal. MLD is a recessive inherited disease.

Treatment Centers & Support

If you have a child diagnosed with early onset* MLD, ask your doctor about treatment with LENMELDY. They will likely refer your child to a specialist who can confirm the diagnosis and help you explore treatment options.
*See full indication.

Qualified Treatment Centers (QTCs)

QTCs are medical centers that have been trained to administer Orchard Therapeutics gene therapy.*
  1. Benioff Children’s Hospital at UCSF (UCSF)
  2. University of Minnesota Fairview (UMN)
  3. Children’s Hospital of Philadelphia (CHOP)
  4. Children’s Healthcare of Atlanta (CHOA)
  5. Texas Children’s Hospital, Baylor University (TEXAS)
* All treatment centers are currently awaiting final confirmation.
  QTCs are independently owned and operated. Orchard Therapeutics does not have oversight over any QTC or the medical care they provide. Contact the QTC or Orchard Assist for additional information.
  Inclusion of a QTC on this map does not represent an endorsement, referral, or recommendation from Orchard Therapeutics. It is the sole discretion of patients and their healthcare professional to determine which QTC may be the best fit for them.
  Please note that the circumstances of coverage may vary based on the QTC. An Orchard Assist representative may be able to provide information about insurance coverage.

Orchard Assist: Growing Together

Your journey begins here

Orchard Assist is here to help you navigate the services and support available to families embarking on gene therapy. With Orchard Assist, you can get help with questions regarding your insurance coverage, support, and treatment journey planning, as well as a dedicated representative supporting you along the way.

What you can expect from Orchard Assist

How health insurance works: Your representative will help your family with understanding what is covered, determining what your out-of-pocket expenses might be, and if travel and lodging are covered in your plan.

Benefits investigation and prior authorization: Your representative may help you understand what is covered for treatment.

Treatment journey planning: Everyone’s treatment journey is different, and Orchard Assist is here to help you at every step of the way, before and
after treatment.

Contact Orchard Assist today at 833-ORCHAST (833-672-4278) or visit for more information



LENMELDY is a one-time gene therapy developed to treat children with pre-symptomatic late infantile, pre-symptomatic early juvenile and early symptomatic early juvenile, referred to as early-onset, metachromatic leukodystrophy (MLD). MLD is caused by a defect in the arylsulfatase A (ARSA) gene, which causes the body to produce reduced or no ARSA enzyme. LENMELDY is made specifically for each child, using the child’s own blood stem cells, and adding functional copies of the ARSA gene to their cells. This may allow you to produce sufficient ARSA enzyme to stop or slow the progression of MLD symptoms.